| 1 |  StellariumA free open source planetarium for your computer. | 26.3 | Open source | September 28, 2026 | — | 118K ↓ |
| 2 |  KiCadA Cross Platform and Open Source Electronics Design Automation Suite | 10.0.6 | Open source | August 30, 2026 | — | 126.7K ↓ |
| 3 |  QuartoQuarto® is an open-source scientific and technical publishing system built on Pandoc | 1.10.19 | Open source | October 6, 2026 | — | 46K ↓ |
| 4 |  Qalculate!A highly versatile desktop calculator, with support for units, physical constants, uncertainty propagation, symbolic calculations, etc. | 5.13.2 | Open source | October 11, 2026 | — | 50.3K ↓ |
| 5 |  JASPA Fresh Way to Do Statistics | 0.99.0 | Open source | October 21, 2026 | — | 12.2K ↓ |
| 6 |  OpenChromOpen Source software for chromatography, spectrometry and spectroscopy | 1.6.38 | Open source | October 23, 2026 | 257.8 MB | 24.6K ↓ |
| 7 |  Klayout - Layout Viewer And EditorKLayout is a GDS and OASIS file viewer. | 0.30.12 | Open source | August 26, 2026 | 316.4 MB | 17.7K ↓ |
| 8 | SscilabScilab is free and open source software for numerical computation providing a powerful computing environment for engineering and scientific applications. | 2025.0.0 | Open source | April 30, 2025 | 205.6 MB | 28.6K ↓ |
| 9 |  AvogadroAvogadro is an advanced molecular editor designed for cross-platform use in computational chemistry, molecular modeling, bioinformatics, materials science, and related areas. It offers flexible rendering and a powerful plugin architecture. | 1.2.0 | Open source | November 5, 2021 | 11.3 MB | 5.5K ↓ |
| 10 |  fendArbitrary-precision unit-aware calculator | 1.5.9 | Open source | October 21, 2026 | — | 5.9K ↓ |
| 11 |  gnuplotInteractive function plotting utility | 6.0 patchlevel 4 | Other licence | December 24, 2025 | 33.1 MB | 3.7K ↓ |
| 12 |  pyzoThe Interactive editor for scientific Python | 4.22.0 | Open source | August 5, 2026 | — | 6.9K ↓ |
| 13 |  nteractnteract is an open-source organization committed to creating fantastic interactive computing experiences that allow people to collaborate with ease. | 0.28.0 | Open source | September 7, 2021 | — | 18K ↓ |
| 14 |  RtoolsRtools is a toolchain bundle used for building R packages from source (those that need compilation of C/C++ or Fortran code) and for building R itself. | 4.5.6768 | Open source | February 7, 2026 | 561.6 MB | 581.1K ↓ |
| 15 |  SpeedCrunchA high-precision scientific calculator featuring a fast, keyboard-driven user interface. | 1.1 | Open source | October 23, 2026 | — | 25.1K ↓ |
| 16 |  GeoGebra ClassicApps bundle including free tools for geometry, spreadsheet, probability, and CAS | 6.0.933 | Proprietary | October 19, 2026 | — | 355.3K ↓ |
| 17 |  Nelsonmulti-paradigm programming language and numeric computing environment. | 1.16.0.5575 | Open source | December 30, 2025 | — | 2.9K ↓ |
| 18 |  insectA high precision scientific calculator with full support for physical units | 5.7.0 | Open source | June 11, 2023 | — | 482 ↓ |
| 19 |  GeoGebra Graphing CalculatorGraph functions, investigate equations, and plot data with our free graphing app | 6.0.933 | Proprietary | October 19, 2026 | — | 146.9K ↓ |
| 20 | Gghidraa software reverse engineering (SRE) framework | 12.2-20261016 | Open source | | — | 241K ↓ |
| 21 |  HopsanA free multi-domain system simulation tool developed at the division of Fluid and mechatronic systems at Linköping university. | 2.24.4.20260918.1254 | Open source | September 21, 2026 | — | 1K ↓ |
| 22 |  Jamovi DesktopOpen statistical software for the desktop and cloud | 28.14.0.0 | Open source | October 23, 2026 | — | 54.3K ↓ |
| 23 |  AAS WorldWide TelescopeTool for showcasing astronomical data and knowledge | 6.1.2 | Open source | August 4, 2022 | 105.3 MB | 945 ↓ |
| 24 |  Maxima computer algebra systemA Computer Algebra System | 5.49.0 | Open source | April 10, 2026 | 164.0 MB | 35K ↓ |
| 25 |  CloudCompare3D point cloud and mesh processing software | 2.13.2 (07-06-2024) | Open source | August 9, 2025 | 342.6 MB | 40 ↓ |
| 26 |  G*PowerGPower is a tool to compute statistical power analyses for many different t tests, F tests, χ2 tests, z tests and some exact tests. | 3.1.9.7 | Free | November 13, 2024 | — | 5.3K ↓ |
| 27 |  JuliaJulia is a high-level, high-performance, dynamic programming language. | 1.24.0.0 | Open source | October 25, 2026 | — | ★ 49.2K |
| 28 |  JuliaJulia is a high-level, high-performance, dynamic programming language. | 1.13.2 | Open source | October 15, 2026 | 170.2 MB | ★ 49.2K |
| 29 |  SirilThe Siril image processing software for amateur astronomy. | 1.2.6 | Open source | April 1, 2025 | 79.6 MB | 1.7K ↓ |
| 30 |  LabPlot2FREE, open source and cross-platform Data Visualization and Analysis software accessible to everyone and trusted by professionals | 2.12.1 | Open source | August 18, 2025 | 96.7 MB | 4.4K ↓ |
| 31 | Ffree42Free42, an HP-42S Calculator Simulator | 3.4 | Open source | | 4.8 MB | 4.4K ↓ |
| 32 | VveuszScientific plotting and graphing program, designed to produce publication-ready 2D and 3D plots. | 4.2.1 | Open source | | — | 3.9K ↓ |
| 33 |  KnitCalcKnitting calculator | 1.9.2 | Open source | September 3, 2026 | — | 305 ↓ |
| 34 |  PositronA next-generation data science IDE | 2026.10.1 | Proprietary | October 20, 2026 | 531.1 MB | ★ 4.3K |
| 35 | OOctaveScientific Programming Language | 11.3.0 | Open source | June 6, 2026 | 566.9 MB | — |
| 36 | SSMath StudioTiny, but powerful mathematical program with WYSIWYG editor and complete units of measurements support. | 1.5.0-9678 | Proprietary | July 1, 2026 | 3.6 MB | 1.7K ↓ |
| 37 |  Serial StudioThe universal dashboard for embedded systems. | 3.1.7 | Proprietary | July 15, 2025 | — | ★ 7.3K |
| 38 |  PaperlibAn open-source simple academic paper management tool for computer science. | 3.1.12 | Open source | September 28, 2025 | 82.5 MB | ★ 2.3K |
| 39 |  Arduino IDE RCArduino IDE (RC version) | 2.0.0-rc9.3 | Open source | September 6, 2022 | 165.0 MB | ★ 3.3K |
| 40 |  LibrePCBCreate electronics the easy way. | 2.1.1 | Open source | June 12, 2026 | 55.9 MB | ★ 3K |
| 41 |  Finite Element Method MagneticsMagnetics, Electrostatics, Heat Flow, and Current Flow | 4.2 | Other licence | June 25, 2024 | 7.9 MB | 953 ↓ |
| 42 | Sserial-clonerMolecular Biology software. Provides tools with an intuitive interface that assists you in DNA cloning, sequence analysis and visualization. | 2.6.1 | Free | | 11.2 MB | 867 ↓ |
| 43 |  KalkerKalker is a calculator program that supports user-defined variables, functions, derivation, and integration. | 2.2.3 | Open source | August 17, 2026 | — | ★ 1.9K |
| 44 |  LibrePCBCreate electronics the easy way. | 2.0.0-rc1 | Open source | January 26, 2026 | 56.6 MB | ★ 3K |
| 45 |  NumaraSimple notepad calculator built on Electron, powered by Math.js | 7.6.3 | Open source | October 24, 2026 | — | ★ 286 |
| 46 |  JASPJASP is cross-platform software that allows you to conduct statistical analyses. | 0.98.85.0 | Open source | October 13, 2026 | — | ★ 1K |
| 47 |  OpenHantek6022DSO software for Hantek USB digital signal oscilloscopes 6022BE / BL. | 3.4.0 | Open source | March 29, 2025 | — | ★ 1.1K |
| 48 |  Horizon EDAHorizon is a free EDA package | 2.7.2 | Open source | March 29, 2026 | — | ★ 1.3K |
| 49 |  pandoc-plotA pandoc filter to generate figures from source code. | 1.9.2 | Open source | August 23, 2026 | — | ★ 260 |
| 50 |  OpentronsSoftware for writing protocols and running them on the Opentrons Flex and Opentrons OT-2 | 10.1.0 | Open source | October 16, 2026 | 394.0 MB | ★ 526 |