COPASI: baixar versions anteriors

Bug Fixes
- Command Line (CopasiSE)
- No files are created or modified when the option --validate is given.
- Simulation Engine
- Time Course Task: The methods RADAU5 not correctly supports the option Suppress Output Before ...
- Time Course Task: The hybrid methods Hybrid LSODA & Hybrid Runge-Kutta now supports automatic step size correctly.
- Optimization and Parameter Estimation Tasks: The method Praxis now correctly terminates if the if solution is within the tolerance.
- Parameter Estimation Task: The Method Evolution Strategy (SRES) checks not the functional constraints like other methods.
- Metabolic Control Analysis and Linear Noise Approximation Tasks: The result now contains the Steady-State result.

New Features since COPASI 4.47 (Build 309)
- This is only a bug fix release there are no new features
Bug Fixes and Enhancements since COPASI 4.47 (Build 309)
- Graphical User Interface (CopasiUI)
- The Time Scale column is now always positive in all tabs containing information about a Jacobian.
- Simulation Engine
- The pseudo random number generation and sampling of distribution is now done with classes provided by the C++ standard.
- Standards
- SBML: Fixed crash when loading a model containing unsupported delays.
- Language Binding
- Assured that all warnings created during import of SBML files are accessible.

New Features since COPASI 4.46 (Build 300)
- Simulation Engine
- Multi threading for population based optimization methods Differential Evolution, Evolutionary Programming, Evolution Strategy (SRES), Genetic Algorithm, Genetic Algorithm SR, Particle Swarm, and Scatter Search speeding up optimization and parameter estimation tasks.
- Command Line (CopasiSE)
- Added option to import and export task settings.
Bug Fixes and Enhancements since COPASI 4.46 (Build 300)
- Graphical User Interface (CopasiUI)
- Opening files from URL when clicking on a link on a website is again functional.
- Tool Profile Likelihood: This tool now also works with just one parameter.
- Tool Create Events from Time Series Experiment allows now the selection of the experiment if multiple experiments are specified.
- Scan Sub Task Output: The tool tips for the check boxes have been corrected.
- Parameter Estimation: Improved behavior when stopping the process to return complete plots.
- Simulation Engine
- Time Course RADAU5: Improved method to properly support multi threading.
- Optimization Scatter Search: Fixed issue detecting improvements in solution.
- Increased stack size under Windows to prevent randomly occurring access violations.

New Features since COPASI 4.45 (Build 298)
- Graphical User Interface (CopasiUI)
- Parameter Estimation: Start in Steady State can now be selected per experiment..
Bug Fixes and Enhancements since COPASI 4.45 (Build 298)
- Graphical User Interface (CopasiUI)
- Parameter Overview: Fixed crash occurring when changing local reaction parameters.
- Optimization and Parameter Estimation: Fixed editing Display Population checkbox.
- Global Quantity: Fixed potential crash when copying of a global quantity with an assignment containing a piece wise expression.
- Load Parameter Sets: Fixed crash when loading additional parameter sets stored in a separate file.
- Reactions: Fixed mapping of 2 substrate kinetics for reactions of the form 2 * Y → ...
- Functions: Fixed copying of functions containing notes.
- Simulation Engine
- Time Course: Fixed problem with event triggers evaluating to NaN.
- Time Course: Improved root finding to determine event firing.
- Time Course: Fixed initial event detection if the Start in Steady State is selected.
- Time Course: Fixed detection of non integer stoichiometry for stochastic or hybrid algorithms.
- Optimization and Parameter Estimation: Reaction parameters mapped to global quantities were not correctly loaded.
- Scan: Fixed behavior of Continue from Current State.
- JIT Compilation: Fixed crash occurring occasionally on Windows.
- Standards
- COMBINE Archive: Fixed naming of experiment data files for Parameter Estimation.
- SBML: Assure that the selected render information is exported.

New Features since COPASI 4.44 (Build 295)
- Graphical User Interface (CopasiUI)
- Added a new tool which attempts to convert ODEs into reactions.
- Added a menu entry which allows definition and subsequent execution of user defined tools.
- Standards
- SBML Import added an option determining how to handle the import of initial values initial references.
Bug Fixes and Enhancements since COPASI 4.44 (Build 295)
- Graphical User Interface (CopasiUI)
- Optimization and Parameter Estimation: Whether to display the population dynamics is now part of the problem specification.
- Fixed deletion of plots in the plot overview.
- Fixed issue where event targets where not longer added to plots, reports, and time series.
- Fixed crash occurring when switching the plot engine to: Qt DataVizualization (surface) for non surface plots.
- Improved labels for surface plots which where limited to 2 decimal digits.
- Fixed problem with notes of global quantities occurring when copying.
- Time course Method Hybrid (RK-45): Selecting the partitioning strategy: user defined and selecting the deterministic reactions caused a crash.
- Fixed delay during start on some Windows 11 installations caused while saving the known MIRIAM resources.
- Functions: It is not longer permitted to copy mass action kinetics.
- Fixed crash occurring when repeatedly deleting parameter sets.
- Fixed problem deleting multiple global quantities.
- Fixed crash when deleting interdependent global quantities.
- Command Line (CopasiSE)
- The argument to the option --report-file is now taken relative to the current working directory.
- Steady-State: Added warning message indicating that no steady-state was found.
- Simulation Engine
- MCA: Fixed scaling for small compartment volumes.
- Steady-State: Fixed occasionally occurring problem calculating the target criterions for models containing moieties, which lead to not finding a steady-state.
- Events: Fixed crash caused by invalid trigger expression.
- Time Course: Fixed output of all steps when the duration is negative.
- Parameter Estimation: Non existing constraint objects will lead to a warning message.
- Standards
- SED-ML: Improved import of time course option initial time and number of points.
- SBML: Improved import of reaction IDs used in multiple assignments.
- SBML: Improved import of files containing reaction kinetics with missing parameters.